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And tirzepatide itself has demonstrated significant improvements in metabolic parameters beyond weight loss, so finding an alternative that matches its metabolic profile is challenging

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Importantly, patients using transdermal medications should avoid exposing the patch to external heat sources such as heating pads, electric blankets, hot tubs, saunas, or prolonged direct sunlight, as heat can increase drug absorption and potentially cause overdose

A: Current oral semaglutide has significant absorption limitations, reducing its weight loss efficacy compared to injectables