Mice lacking these eight amino acids exhibited autism-like behaviors, linking the microexon loss directly to autism
doi: 10.1016/j.cell.2010.03.014 288 QiuSQWaaijerSJHZwagerMCde VriesEGEvan der VegtBSchroderCP
Its primary mechanism is the upregulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) two of the most important proteins governing neuronal survival, plasticity, and the formation of new neural connections
These mechanisms alter chromatin structure, modulating gene expression related to neuronal plasticity and responses to stress, depression, and antidepressants 9,129
Effects of arachidonic acid metabolites on cardiovascular health and disease
Arthur and Bonnie Ennis Foundation, Decatur, IL, USA