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23,24 A post hoc analysis of the Look AHEAD trial reported that at least 10% weight loss in the first year was associated with a 21% lower risk of major adverse cardiac events

Accordingly, since many participants had baseline clinical kidney parameters in the normal range, effects on albuminuria cannot be directly generalized to people with more advanced stages of CKD

Public Health Nutrition, 23(2), 286294

GLP-1 receptor agonists were associated with substantial decreases in SBP for dulaglutide and albiglutide relative to placebo in a network meta-analysis of 60 clinical trials

Semaglutide is a GLP-1 receptor agonist that suppresses appetite, delays gastric emptying, and improves glucose-dependent insulin secretion

doi: 10.3390/foods14030373