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The specific absence of SIRT2 in RTECs aggravates renal fibrosis in UUO mice, while SIRT2 overexpression has the opposite effect

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As COL IV genes are expressed by the animals body wall muscles in addition to their DTCs 44 , to avoid any confounding effects that could result from systemic manipulations of COL IV levels, we used a strain that allows us to specifically interfere with DTC COL IV production by RNAi

91 SahathevanS.KarupaiahT.KhorB.Sadu SinghB.Mat DaudZ.FiaccadoriE.et al (2021)

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