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Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

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This enabled us to assess whether the structural differences and conformational dynamics observed in the Cagri and rAmy bound AMYR structures alter the nature of Gs protein interaction (Supplementary Fig

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Studies have explored the role of glutathione in mitigating age-related damage and promoting healthy aging

The pathway is sometimes referred to as a cycle, but according to its classical representation, it is a linear sequence that links reduction of H 2 O 2 , catalysed by APX, to oxidation of NADH or NADPH, catalysed by MDHAR and GR (Fig