Semaglutide is generally not known to cause high blood pressure
Only afterward does the question arise: how long does semaglutide remain in the body
These medications are injected either daily or weekly, and they work by: Making you feel fuller for longer Slowing down your digestion Improving how your body uses blood sugar GIP is also a natural hormone that influences blood sugar and appetite

Contact your healthcare provider if you experience: Persistent constipation lasting more than three days despite dietary modifications and adequate hydration Severe or persistent diarrhea (more than six loose stools daily or lasting beyond 48 hours) Rectal bleeding, even if minor, particularly if bright red blood is noted on toilet paper or in the toilet bowl Black, tarry, or maroon-colored stools (which may indicate bleeding higher in the digestive tract) Severe abdominal pain, cramping, or bloating that interferes with daily activities Signs of dehydration including dark urine, dizziness, or decreased urination Painful bowel movements or a sensation of incomplete evacuation Visible or palpable lumps around the anus Persistent anal pain, itching, or discomfort Seek immediate medical attention for: Severe, persistent abdominal pain, especially if radiating to the back (may indicate pancreatitis) Right upper quadrant pain, fever, or yellowing of skin/eyes (may indicate gallbladder disease) Heavy rectal bleeding or passage of large amounts of blood Severe abdominal pain with fever, persistent vomiting, abdominal distension, and inability to pass stool or gas (may suggest bowel obstruction) Signs of severe dehydration including confusion, rapid heartbeat, or inability to keep fluids down Important: If you suspect pancreatitis (severe abdominal pain, often radiating to the back, with or without vomiting), stop taking Zepbound immediately and seek urgent medical care

While these shifts often support metabolic health, they may in some slow motility and predispose the gut to imbalances if not supported
Spectrum of mast cell activation disorders