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The first option has for instance been explored by targeting B cells in gMG, RA (NCT00931086), ITP, CIDP, Sjgrens syndrome (NCT03154385, NCT02531538, NCT03905525), and TED (NCT00212726) [383, 384] with therapeutic mAbs directed against CD20, B-lymphocyte stimulator protein, and CD40

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Gut protection: As its origin hints, BPC-157 works well in animal models of stomach ulcers, inflammatory bowel disease, and painkiller-caused gut damage

In a healthy intestine, autoimmune and inflammatory reactions are kept under control because SCFAs create a correct balance between Treg cells and Th17 cells

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doi:10.1080/14656566.2024.2356254