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The matrix physically blocks drug penetration, and bacteria inside biofilms alter their metabolic state in ways that make standard antibiotics far less effective
For instance, its C-terminus showcases a trans-3-hexenoic acid group alteration, a change sometimes referred to as an omega-amino acid modification, which is suggested to bolster the peptide's resilience to enzymatic degradation
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The amplitude, polyphasic changes, and the proximal and distal CMAP latencies were recorded, and the nerve conduction velocity was calculated according to previous studies [41, 43]
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