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FDA-approved for type 2 diabetes and for reducing the risk of major adverse cardiovascular events in certain adults with type 2 diabetes and established cardiovascular disease

Instead, it uses the changes of pressure from the movement in the skeletal muscles, the respiratory system, and the contraction of smooth muscle that is generally found in your organs (1)

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10.1016/j.neuropharm.2011.07.036 40

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Because chronic inflammation is strongly associated with metabolic dysfunction, this mechanism has generated interest among researchers studying metabolic disease