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Side effects tend to be more noticeable at initiation or higher doses via subcutaneous injection

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Physiol Rev 94:739777 Last K, Maharaj L, Perry J, Strauss S, Fitzgibbon J, Lister TA, Joel S (2006) The activity of methylated and non-methylated selenium species in lymphoma cell lines and primary tumours

Monitoring includes regular body composition analysis (DEXA or similar), fasting glucose and insulin, HbA1c, IGF-1 levels, lipid panels, and clinical assessments

It also aids energy levels , recovery, and overall wellbeing in ways that extend beyond the direct hormonal effects