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Neurological diseases, including strokes, Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), have been correlated with increased oxidative stress [29, 30]

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior

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J Biol Chem 247:31703175

We find that ROS production correlates to a binding mode where two imidazole nitrogen atoms coordinate to the copper-ion leaving the remaining binding sites free for interaction with e.g