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Carmot Therapeutics is a U.S.-based biotech company focused on developing incretin-based therapies, including CT-388 (a weekly injectable dual GLP-1/GIP agonist), an oral small-molecule GLP-1 agonist (CT-996), and another injectable GLP-1/GIP candidate (CT-868)

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In this study, researchers found that mice with a specific genetic mutation produced too much glutathione

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In the present study, PFOS time dependently increased IRE1 (an ER stress marker) expression, indicating ER stress induction, which could be eliminated by l-Carnitine through its antioxidative activity