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Treatment with gonadotropin-releasing hormone (GnRH) analogues, estrogen supplements, oral contraceptives with low estrogen doses or progesterone alone achieves satisfactory prevention, suggesting the importance of maintaining adequate hypothalamic-pituitary axis regulation in CVS.58,59 The recognition of this subtype highlights the importance of a deeper understanding of the pathologic mechanisms of CVS, consequently providing highly efficacious personalized treatment

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