The NHS says tirzepatide (Mounjaro) and semaglutide (Wegovy) are weight-loss injections that help reduce appetite and slow stomach emptying, and that they should only be prescribed alongside programmes that support healthier eating and physical activity
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For example, bariatric surgery (particularly Roux-en-Y bypass surgery) is contraindicated in many genetic obesity syndromes as it does not reverse the strong hypothalamic drive to eat and continued overeating can be harmful
Comparison with peers and trials
To understand where these fit, it helps to look at what compounding pharmacies can legally do, what recent FDA shortage decisions changed, and how compounded products actually compare to brands
This makes it the go-to choice for acute, severe pain where a fast onset of relief is critical