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Critically, we demonstrated that suppression of SLC7A11 transcription results from mut-p53 binding and interfering with the activity of the master antioxidant transcription factor NRF2, a mechanism which is separate from the transcriptional regulation of SLC7A11 by wt-p53 described by Jiang et al

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Doussau de Bazignan M, Turleau C: Embryonic testicular regression syndrome and severe mental retardation in sibs

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10.2165/00003495-200161110-00008 38 CurrieC

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