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In a phase I clinical study, the GSH-PEG liposomal methylprednisolone (2B3201) was found to be safe [45]
It is interesting to note that when combined with conventional chemotherapy drugs such as doxorubicin, cyclophosphamide, and taxanes, these fatty acids improve cancer cells sensitivity to cytotoxic drugs, lessen side effects like cachexia, neuropathy, or myelosuppression, or overcome multidrug resistance (168)
It has also been discovered to be necessary for the development and maintenance of skeletal and muscle tissue, and to raise IGF-1, or Insulin-like Growth Factor 1
584(2): 15765 Bhuiyan AK, Jackson S, Turnbull DM, et al
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