Nature 535:111116
There are many topical depigmenting agents such as hydroquinone, glycolic acid, arbutin, kojic acid, Vitamin C, Vitamin E and niacinamide
Alpha-Lipoic Acid Alpha-lipoic acid is a multifunctional compound in its ability to serve as a direct scavenger of free radical species and to also help in the regeneration of endogenous antioxidants such as glutathione
The most common and severe form, infantile or nephropathic cystinosis, constitutes roughly 95% of all cases and is associated with kidney failure at 910 years of age [2]
It inhibits the reuptake of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), leading to prolonged monoaminergic neurotransmission
Systemic safety data in humans is limited