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For adults with a BMI of 40 kg/m2 or higher or those with a BMI of 35 kg/m2 or higher with obstructive sleep apnea or prediabetes, Apovian recommends strongly considering bariatric surgery as a first-line therapy due to very low complication rates and robust and durable weight loss

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Potential Risks and Side Effects The FDA states that compounded drugs containing AOD-9604 carry a significant risk for immunogenicity

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124 Interestingly, KC death has been suggested to act altruistically to facilitate the recruitment of effector cells during inflammation