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doi: 10.1517/14656566.2013.824966 18 NauckMAQuastDRWefersJMeierJJ

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Enrolment into the SAD and MAD cohorts was sequential

In the STEP-1 trial, 1,961 patients were followed for 68 weeks and underwent randomization to semaglutide or placebo plus lifestyle intervention resulting in14.9% weight loss in the semaglutide group versus 2.5% in the placebo group [33]