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Several mechanisms have been proposed to help explain this complex process, including (i) the persistence of HIV viral reservoirs, (ii) the dysregulation of intestinal mucosa and microbial translocation, (iii) the depletion of regulatory T (Treg) cells, and (iv) co-infection with other viruses [13]
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Along with the direct activation of matrix metalloproteinase-2 (Bescond et al, 1999), vascular damage might also result from an impairment of the tertiary structure of connective tissue protein, because of the reduced degree of cross-linkage between collagen and fibrin monomers (Lubec et al, 1996a
The peptide industry was given just 10 minutes before the committee to present arguments that the six peptides were safe
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