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A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.) All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA , probably superior to traditional versions, so be happy to spot it on the ingredient list
For mild cases, several home remedies can alleviate symptoms: Warm Baths: Soaking in warm water can reduce discomfort and soothe the anal area
Inulin , a prebiotic, helps strengthen the skin barrier while glycerin and squalane provide comfortable hydration without a greasy effect
Salaun C., et al., Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation
Lyophilized (freeze-dried) peptides should be stored in a freezer at -20C or below for long-term stability