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By increasing serotonin availability in synaptic spaces, it: Improves mood and reduces symptoms of depression Reduces anxiety and associated physical symptoms Helps regulate sleep and appetite in patients with mood disorders Escitalopram is taken orally once daily and is metabolised primarily in the liver by cytochrome P450 enzymes (mainly CYP2C19, with minor contributions from CYP3A4 and CYP2D6)

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The mitochondrial CK isoform exists in the intermembrane space of the mitochondria where it can convert from an octameric to a dimeric form (Dolder et al