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notably, those changes correlated with higher peripheral inflammation (plasma cytokines) [127, 128]

This regulatory effect restores the activation of the NF-B signaling pathway in intestinal epithelial cells mediated by mutant NOD2 and promotes the production of proinflammatory cytokines (149)

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Addressing these gaps through well-designed, large-scale clinical trials with standardized protocols and extended follow-up periods will be essential to clarify the therapeutic relevance of astaxanthin in neurodegenerative disorders

Deciphering the conformations of glutathione oxidized peptide: a comparative NMR study in solution and solidstate environments

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