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Curcumin & Astaxanthin Curcumin enhances the effects of pharmaceutical 5-AR inhibitors (Luo et al., 2021), while astaxanthin combined with saw palmetto shows potent in-vitro 5-AR inhibition (Anderson, 2005)

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Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2

4-OHE2 itself is an estrogen receptor ligand slower glutathione clearance of 4-OHE2-derived reactive species extends both their genotoxic and their receptor-activating potential at target tissues

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