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Emerging next-generation options Several next-generation therapies are currently under clinical trials for weight loss

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A 2022 meta-analysis in Frontiers in Endocrinology pooled 14 trials of GLP-1 receptor agonists and antioxidant outcomes and concluded that GLP-1 agonists reduce oxidative stress markers independent of weight loss or glucose lowering

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Therefore, If there is significant weight reoccurrence, if there is significant additional weight to lose, or if we need a more permanent solution, I do not recommend medical therapy