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As a result, VE deficiency and the intake of unsaturated fatty acids may contribute to the development of MC.17 Changes to mast cells in the colon are involved in the pathogenesis of MC Mast cells secrete a variety of cytokines in the intestine and participate in the regulation of immunity

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108, 371381 10.1172/JCI12348 [DOI] [PMC free article] [PubMed] [Google Scholar] 66.Kadowaki, T., Fujita-Yamaguchi, Y., Nishida, E., Takaku, F., Akiyama, T., Kathuria, S.et al

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This marks the first known clinical demonstration of the therapeutic potential of TRPC inhibition in humans an exciting milestone for the field