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Further to validate if our findings have broader implications, we compared our High ADA and Low ADA metabolomics datasets with the transcriptomic datasets with high (GSE15573) or low (GSE97779 and GSE10500) expression of ADA

Front Immunol (2020) 10:2969/FULL

doi:10.12816/0006054 [30] Tamer G, Arik S, Tamer I, Coksert D

Glutathione is a scavenger that we naturally produce to help preserve our cells from damage

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In fact, in physiological conditions, AGEs are formed very slowly while, in particular conditions like hyperglycemia, insulin resistance, obesity, aging, oxidative stress and hypoxia, their formation process is accelerated [33]