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*Correspondence: Li-Chen Gao, [email protected] This article was submitted to Pharmacology of Anti-Cancer Drugs, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

this dose also provoked the largest percentage of weight loss though the once-weekly injectable dose of semaglutide at 1 mg was similarly effective.35 Cardiovascular Protection In addition to blood glucose and weight loss benefits, GLP-1s have shown effectiveness in improving cardiovascular outcomes and reducing the risk of major cardiovascular events.36 The SELECT trial showed that semaglutide 2.4 mg weekly significantly reduced major adverse cardiovascular events, heart failure-related hospitalizations, cardiovascular deaths, and all-cause mortality in adults with overweight or obesity and established CVD, including those with and without heart failure

K., Kohli, S., Mustian, K