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In contrast, the combination of CB-839/telaglenastat with multiple tyrosine kinase receptor inhibitor cabozantinib did not improve the efficacy of cabozantinib in patients with advanced RCC in the CANTATA phase II randomized clinical trial (NCT03428217), although it was well tolerated [163]

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This dual action caught the attention of scientists studying wound healing, who began exploring whether these protective and regenerative properties could translate to skin repair applications

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