Some are even classified by the FDA as 510(k) class II medical devices
It is researched in preclinical research for its interaction with GABAergic and serotonergic signaling pathways
Crescenz VA Medical Center in Philadelphia, and the University of Pennsylvania School of Medicine, tested a new and noninvasive way of delivering GSH through nasal sprays, and used proton magnetic resonance spectroscopy ( 1 H-MRS) to measure CNS uptake of GSH
Caution is advised for individuals with specific health conditions, like asthma
Sources: Ahokas EK, Hanstock HG, Kyrlinen H, Ihalainen JK
Contraindications and Precautions Do NOT use AOD-9604 if you: Are pregnant, trying to conceive, or breastfeeding (no safety data in pregnancy/lactation) Have active cancer or history of malignancy (peptide effects on existing cancer unknown) Are under 18 years of age (pediatric safety not established) Have known hypersensitivity to peptides or benzyl alcohol (in bacteriostatic water) Have severe kidney or liver disease without physician clearance Use with caution and enhanced monitoring if you have: Diabetes or glucose metabolism disorders (monitor blood sugar closely despite no expected impact) Cardiovascular disease (comprehensive cardiac evaluation recommended) Thyroid disorders (monitor thyroid function during therapy) History of migraines (may increase headache frequency in susceptible individuals) Drug Interactions Limited formal drug interaction studies exist for AOD-9604
