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On December 24, 2025, a 32-year-old Melbourne woman named Megan Hancocks injected herself with what she believed was retatrutide, the most anticipated weight-loss drug in the world
Proper testing reduces risks and improves results
The thyroid safety concern stems from preclinical research in rodents, where semaglutide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)
Prescripton GLP-1 drugs can be cost-prohibitive and can sometimes cause severe side effects like nausea
Barkley also didn't share if he was overweight or obese before starting on the drug to live longer, but an obesity expert previously told Insider that obesity can be life-threatening and those with more excess weight, particularly those who are severely obese, have a shorter life expectancy on average