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While some of the studies we have described here have pointed to broader metabolic disturbances like mitochondrial dysfunction or decreased energy metabolism, these results have not been replicable and have focused on only a small subset of compounds

Scientists engineered this analog by replacing the third amino acid (glutamic acid) with arginine and adding a 13-amino-acid extension peptide to its N-terminus

Robert SA, Rohana AG, Shah SA, Chinna K, Wan Mohamud WN, Kamaruddin NA

May 2012;37(5):1074-1084

However, its crucial to ask ourselves: Whats causing this pain