Semaglutide can reduce B12 absorption by slowing gastric transit, but not all patients develop deficiency
For these localized applications, systemic absorption may matter less than direct contact with digestive tissues
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Illnesses Any illness or condition that affects the digestive system can result in a B12 deficiency because the vitamin is bound to the protein molecules in your food and is released and absorbed by the body during digestion
Therefore, the two peptides may be used to provide a rapid onset of action with Ipamorelin and prolonged effects with CJC-1295
Clin Chim Acta (2020) 502:21421