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Medical uses for methylene blue Methylene blue is approved by the Food and Drug Administration (FDA) to treat a blood disorder called methemoglobinemia

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TBK1-mediated phosphorylation of NDP52 facilitates direct interaction with the FIP200/ULK1 complex thus enabling spatial proximity to ubiquitinated cargo to drive autophagosome biogenesis (43)

SASP: The senescence-associated secretory phenotype refers to molecules released by senescent cells that both help them survive, and that signal immune cell clearance

Anti-estrogen-based endocrine therapies, such as the ER modulator Tamoxifen, ER degrader Fulvestrant, and the aromatase inhibitor Letrozole, have significantly enhanced the survival rates of patients with hormone receptor-positive (HR+) breast cancer [5]

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