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Spermatozoa from GPx4-KO mice contain higher levels of protein thiols compared to WT mice, demon- strating that the stability of the sperm midpiece relies on the presence of mGPx4 and its protein thiol perox- idase activity

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Cardiovascular mortality was defined as deaths resulting from any cardiovascular causes, which include, but are not limited to, cardiac arrest, MI, and arrhythmia