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Before starting B12 supplementation , discuss with your GP if you have existing gastrointestinal conditions or are taking multiple medications

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The anti-adipogenic effect of PGF2 is mediated through prostaglandin F receptor-mediated elevation in intracellular calcium and DNA synthesis [168] and activation of MAPK, causing reduction in PPAR phosphorylation [169]

If your digestive system isn't working properly, oral supplements can be ineffective

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