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The surface receptors on cancer cells engage with ECM components and ECM-bound factors, facilitating cell adhesion and signaling, which in turn regulate a wide array of processes such as proliferation, differentiation, migration (Gonzalez and Medici, 2014)

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These initial results sparked an intensive GST research, which focused on the detoxification of various herbicides and other toxic xenobiotic compounds in plants (Lamoureux and Rusness, 1989

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