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Darifenacin has a 12 fold higher selectivity for M3 compared to M1 & M5, 59-fold greater selectivity for M3 vs M2 & M4 (rxlist.com)
doi: 10.1016/j.physbeh.2015.06.013 136 StalonasP
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Notable observations post-administration include a marked increase in daytime activity, the erasure of circadian rhythms ( Pharmacological intervention Experimental groups were established, each comprising 6 model mice and 6 control mice
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