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DURATION-5 highlighted higher rates of nausea (and subsequent vomiting) with use of exenatide twice daily compared with the once-weekly formulation, with two patients in the twice daily arm reporting severe nausea, compared to none in the once weekly arm [Blevins et al

This article reviews evidence from human clinical trials and animal models, focusing on mechanisms, applications under study, and limitations

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While it may serve as a complementary option for some individuals with metabolic disorders, it should not replace clinically approved therapies

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