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A multicentre retrospective study of 499 patients identified ICI patients with renal cell carcinoma (RCC) in which 80 patients developed severe irAEs warranting treatment cessation, 36 of whom were able to be restarted on an ICI agent and 44 permanently discontinued

Epirubicin cardiotoxicity: an analysis of 469 patients with metastatic breast cancer

They may include: If your diarrhea lasts more than a few days, your doctor might recommend an over-the-counter antidiarrheal medication

Since cell proliferation is influenced by multiple regulatory pathways, including metabolic state, mitochondrial function, and redox balance, additional mechanisms beyond ferroptosis likely contribute to this phenotype

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