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Analytical methods have their own validation and documentation expectations

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Fourth, since the increased risk of incident CVD and adverse outcomes related to elevated UA levels appear to involve UA levels that are in the upper part of reference range of UA level, a reappraisal of reference range of UA by authoritative bodies is required to determine truly physiological concentrations of circulating UA

A., Ngomo, S., & Fernandes, K

TGR5 agonists, which provide anti-inflammatory benefits through the activation of TGR5