Additionally, Ipamorelin appeared to potentially increase the levels of serum leptin, a hormone believed to be involved in regulating energy balance and appetite
This is part of the reason the peptide is so efficient in boosting growth with lower calorie consumption
Researchers such as Johansen suggest that by mimicking this hormone, Ipamorelin may induce the release of growth hormone by anterior pituitary cells but also potentially mediate other actions similar to ghrelin
IGF-DES Receptor Binding Specificity Competitive binding and receptor cross-linking experiments confirmed that both IGF-1 and des-(1-3)IGF-1 bind exclusively to the type 1 IGF receptor in L6 myoblasts, rat vascular smooth-muscle cells, and human lung fibroblasts with des-(1-3)IGF-1 demonstrating greater apparent potency in these assays, attributable to its low affinity for the competing 38 kDa IGFBP rather than differences in intrinsic receptor affinity
Total concentration: 10 mg 2 mL = 5 mg/mL total peptide
Side effects are generally mild and may include temporary redness or swelling at the injection site, nausea, or mild headaches