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Patients should aim for 6-8 glasses of fluid daily (about 1.5-2 litres), adjusting for individual needs, hot weather, or physical activity

Additionally, evening dosing may be more convenient for individuals with busy morning schedules or those who prefer to administer injections in the privacy of their home after work

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Levels below 200 to 250 pg/mL are considered deficient, though symptoms can appear even at slightly higher levels

If the worsening is severe, the dosage may be increased or medication to reduce inflammation may be prescribed