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For example, mice with depleted gut microbiota-achieved through germ-free housing or antibiotic treatment exhibited reduced responses to CTLA-4 blockade immunotherapy

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Exposure occurred in 100 mm glass petri dishes with an average of 30 larvae per dish, with 2 dishes (technical replicates) per exposure

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(PubMed) Seshadri S, Beiser A, Selhub J, et al

Synapse (New York, NY) 75(12):e22221 Wang Z, Zhou L, An D et al (2019) TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice [J]