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Were not going to get into the nitty gritty of B12, but know that its absorption isnt as straightforward as other nutrients

What to Expect with Semaglutide (Ozempic) Treatment Ozempic is typically given as a shot once a week

Long-term use of metformin (for type 2 diabetes) or proton pump inhibitors can also deplete B12 levels over time

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The loss of enterohepatic recirculation would definitely cause an additional loss of 5mcg of B12 that is not recovered from bile

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