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Some people report feeling more tired or nauseous, especially in the first few weeks of treatment

Therefore, one of the most important future directions for the treatment of IBD is the formulation of personalized diet plans based on individuals' immunometabolic status and microbiota profiles

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The disease onset is acute for most patients, but a more prolonged course (more than 2 months of evolution) has been reported in up to 25% of cases [63]

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