While similar, the two drugs have been approved for different treatments, although both are Semaglutide medications which basically work as appetite suppressants
10.1182/blood-2003-09-3198 38 ReayW
The headline results at 80 weeks were: 12 mg dose: average weight loss of 28.3% (approximately 70.3 lbs / 31.9 kg) 9 mg dose: average weight loss of 25.9% (approximately 64.4 lbs / 29.2 kg) 4 mg dose: average weight loss of 19.0% (approximately 47.2 lbs / 21.4 kg) Placebo: average weight loss of just 2.2% Perhaps most striking was the proportion of patients hitting bariatric-surgery-level outcomes: at the highest dose, 45.3% of participants lost 30% or more of their body weight , and 65.3% reduced their BMI to below 30 kg/m meaning they were no longer classified as living with obesity by the end of the trial
This discovery came with years of painstaking research and trial and error in order to effect techniques that would allow for gradual correction of limbs that were bent, short or otherwise deformed
To summarise, normally occurring reactive astrogliosis is in the first instance an intrinsic and evolutionary conserved set of diverse astrocyte responses that are aimed at neuroprotection, maintenance of tissue homoeostasis and preservation of nervous tissue integrity
Laura Davisson, director of West Virginia Universitys medical weight management program, said its a challenge to help her patients pay for the drugs
