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It has been investigated for its potential to treat inflammatory conditions such as gastric and stomach ulcers, inflammatory bowel disease (IBD), and tendon injuries

In a nested case-noncase study by Battini et al, 24 all signal detection methodologies and disproportionality statistics investigating the GLP-1 analogs, in particular, liraglutide and glicazide, agreed on its statistically significant potential antidepressant effect

1 A 2025 narrative review by Varughese and colleagues describes the broader animal-data picture for GLP-1 receptor agonists: lower fetal weight, delayed bone development, skeletal differences, and abnormalities in internal organs in animals exposed during gestation

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SGLT2 inhibitors are also emerging as an essential class of drugs due to their ability to reduce blood sugar levels and prevent complications like kidney disease

Hodge RD, Nelson BR, Kahoud RJ, Yang R, Mussar KE, Reiner SL, et al