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Researchers also study its effects on metabolic function, metabolism, energy expenditure, insulin sensitivity, and insulin resistance

Furthermore, one article suggests that it suppresses caspase-dependent apoptosis (decreases caspase activity responsible for programmed cell death) that increases during the process of aging [10]

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Moreover, it has been reported that the increase in excitatory neurotransmitters or intracellular calcium following the activation of voltage- or ligand-gated channels such as the NMDA receptor (glutamate receptor) is considered to be due to the different stimuli that activate the signaling process of CREB (Alberini 2009)