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TABLE 2 Clinical trials with anti-ferroptosis therapeutics

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Laurent C, Eddarkaoui S, Derisbourg M, Leboucher A, Demeyer D, Carrier S et al (2014) Beneficial effects of caffeine in a transgenic model of Alzheimers disease-like tau pathology

All TPP-dependent enzymes contain a highly similar TPP-binding domain and its lack in the TKTL1 protein strongly suggests that it is unlikely that TKTL1 is a TPP-dependent protein capable of catalyzing the transketolase reaction

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2013;8(8):e70933